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Antigenic Specificity | KHDRBS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human KHDRBS1 (NP 006550.1). |
Other Names | [p62; p68; Sam68] |
Gene, Accession # | [KHDRBS1], Gene ID: 10657, NCBI: Q07666.1, UniProt: Q07666 |
Catalog # | MBS8545909 |
Price | $280 |
Order / More Info | KHDRBS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |