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Antigenic Specificity | Mouse Flt-3 |
Clone | [12B6] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes mouse Flt-3 in western blot. Cross reactivity to Flt-3 of other species has not been tested. The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk1 (stem cell tyrosine kinase) and designated CD135, is a member of the class III subfamily of receptor tyrosine kinases. This familay includes KIT, the receptor for SCF, and C-FMS, the receptor for M-CSF. The extracellular region of these receptors contains five immunoglobulin-like domains and the intracellular region contains a split kinase domain. Mouse Flt3 cDNA encodes a 992 amino acid (aa) residue type I membrane protein with a 27 aa residue signal peptide, a 517 aa extracellular domain with 10 potential N-linked glycosylation si |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with purified recombinant mouse Flt-3 extracellular domain. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [mouse Flt-3 (#12B6)], [FLT3; FLT3; FLK2; STK1; CD135; FLK-2; CD135; FLK2; STK1; FLK-2; FLT-3; STK-1] |
Gene, Accession # | [Flt-3], Gene ID: 2322, NCBI: NP_004110.2, UniProt: P36888 |
Catalog # | MBS690599 |
Price | $490 |
Order / More Info | Mouse Flt-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |