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Antigenic Specificity | MAP1LC3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, porcine |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. |
Immunogen | Immunogen: A synthetic peptide of human MAP1LC3B |
Other Names | [LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3] |
Gene, Accession # | [MAP1LC3B], Gene ID: 81631, NCBI: Q9GZQ8.3, UniProt: Q9GZQ8 |
Catalog # | MBS8546647 |
Price | $280 |
Order / More Info | MAP1LC3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |