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Antigenic Specificity | E-Cadherin |
Clone | [2G5-D8-B10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1.56mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the |
Immunogen | Immunogen: Synthetic peptide corresponding to human E-Cadherin protein. Sensitivity: This antibody detects endogenous levels of E-Cadherin and does not cross-react with related proteins. Sequence Similarities: Contains 5 cadherin domains. |
Other Names | [Arc 1; CADH1_HUMAN; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin], [CDH1; UVO; CDHE; LCAM; Arc-1; CD324; CDH1] |
Gene, Accession # | [ECAD], Gene ID: 999, NCBI: NP_001304113.1, UniProt: P12830 |
Catalog # | MBS475592 |
Price | $335 |
Order / More Info | E-Cadherin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |