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Antigenic Specificity | Human MXI1 |
Clone | [MXI1C2a] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 100 ug/ml (1.0 ml) |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts |
Immunogen | n/a |
Other Names | [Homo sapiens MAX interactor 1, mRNA (cDNA clone MGC:9999 IMAGE:3882557), complete cds.; MAD2; MXD2; MXI; MGC43220], [MXI1; MXI1; MXI; MAD2; MXD2; bHLHc11] |
Gene, Accession # | [MXI1], Gene ID: 4601, NCBI: BC012907 |
Catalog # | MBS120419 |
Price | $395 |
Order / More Info | Human MXI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |