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Antigenic Specificity | Phospho-IGF1R-Y1280 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y1280 of human IGF1R |
Other Names | [IGF1R; CD221; IGFIR; IGFR; JTK13; insulin-like growth factor 1 receptor ], [IGF1R; IGF1R; IGFR; CD221; IGFIR; JTK13; IGF-I receptor] |
Gene, Accession # | [IGF1R], Gene ID: 3480, NCBI: P08069.1, UniProt: P08069 |
Catalog # | MBS128424 |
Price | $235, $350, $525 |
Order / More Info | Phospho-IGF1R-Y1280 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |