Edit |   |
---|---|
Antigenic Specificity | TTL (C-term), 232-263 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.33 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TTL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-263 amino acids from the C-terminal region of human TTL. TTL is a cytosolic enzyme involved in theposttranslational modification of alpha-tubulin (see MIM 602529).Alpha-tubulin within assembled microtubules is detyrosinated overtime at the C terminus. After microtubule disassembly, TTL restoresthe tyrosine residues and consequently participates in a cycle oftubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed14571137]). |
Immunogen | n/a |
Other Names | [Tubulin--tyrosine ligase; TTL; TTL] |
Gene, Accession # | [TTL], Gene ID: 150465, NCBI: NP_714923.1, UniProt: Q8NG68 |
Catalog # | MBS9208380 |
Price | $165, $370 |
Order / More Info | TTL (C-term), 232-263 Antibody from MYBIOSOURCE INC. |
Product Specific References | Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) : Erck, C., et al. Cytogenet. Genome Res. 101(1):47-53(2003) Mialhe, A., et al. Cancer Res. 61(13):5024-5027(2001) Ersfeld, K., et al. J. Cell Biol. 120(3):725-732(1993) |