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Antigenic Specificity | Human CD178: Low Endotoxin |
Clone | [10F2] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.5 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | ELISA (EIA), Flow cytometry (FC/FACS), Functional Assays (FN), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD178 antibody, clone 10F2 recognizes the human CD178 cell surface antigen, a 40kDa glycoprotein also known as Fas ligand (CD95L). CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis. Clone 10F2 is reported to block the activity of Fas ligand (Legembre et al. 2002). |
Immunogen | Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [tumor necrosis factor ligand superfamily member 6 isoform 1; Tumor necrosis factor ligand superfamily member 6; tumor necrosis factor ligand superfamily member 6; CD95 ligand; apoptosis (APO-1) antigen ligand 1; apoptosis antigen ligand; fas antigen ligand; Fas ligand (TNF superfamily, member 6); Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble formAlternative name(s):Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL], [FASLG; FASLG; APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; APT1LG1; CD95L; FASL; TNFSF6; APTL; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA] |
Gene, Accession # | [CD178], Gene ID: 356, NCBI: NP_000630.1, UniProt: P48023 |
Catalog # | MBS211247 |
Price | $675 |
Order / More Info | Human CD178: Low Endotoxin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |