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Antigenic Specificity | CD209 (DC-SIGN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CD209 (DC-SIGN) protein. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, cytomegalovirus gB, HCV E2, dengue virus gE, |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.389~393(E-Q-F-L-S)derived from Human CD209 (DC-SIGN). |
Other Names | [CDSIGN; CLEC4L; DC-SIGN] |
Gene, Accession # | [CD209], Gene ID: 30835, NCBI: NP_001138365.1, UniProt: Q9NNX6 |
Catalog # | MBS9403498 |
Price | $200, $255 |
Order / More Info | CD209 (DC-SIGN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |