Human Cystatin B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Cystatin B |
| Clone | [P2F1AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2b k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: Type 1 cystatins are also called stefins which function as intracellular thiol protease inhibitors. Cystatin-B protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. CSTB protein protects proteases leakage from lysosomes. Mutations in Stefin-B gene cause primary defects in patients with progressive myoclonic epilepsy (EPM1), a degenerative disease of the central nervous system. CSTB is overexpressed & elevated in the serum of HCC patients. Cystatin-B in vivo has a polymeric structure which is sensitive to the redox environment. Cystatin-B inhibits bone resorption by down-regulating intracellular cathepsin K activity despite increased osteoclast survival. Protein and mRNA |
| Immunogen | Immunogen: Anti-human CSTB mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSTB amino acids 1-98 purified from E Coli. |
| Other Names | [CSTB; Cystatin B, Mouse Human; Cystatin-B; Stefin-B; Liver thiol proteinase inhibitor; CPI-B; CSTB; CST6; EPM1; PME; STFB], [CSTB; CSTB; PME; ULD; CST6; EPM1; STFB; EPM1A; CST6; STFB] |
| Gene, Accession # | [CSTB], Gene ID: 1476, NCBI: NP_000091.1 |
| Catalog # | MBS140241 |
| Price | $140, $205, $505 |
| Order / More Info | Human Cystatin B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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