beta-Actin (A11) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | beta-Actin (A11) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat, human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | 0.200 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mouse, rat, and human beta-Actin. All eukaryotic cell types express actin. The regulation of the actin cytoskeleton is tightly linked to vital biological properties such as polarity, motility, cell-cell contact, exocytosis and proliferation (1&2). While lower eukaryotes such as yeast, have only one actin gene; higher eukaryotes have several isoforms encoded by a family of genes (3&4). At least six types of actin are present in mammalian tissues and fall into three classes (5). Alpha-actin expression is limited to various types of muscle, whereas beta and gamma are the principle constituents of filaments in other tissues (6). |
| Immunogen | Immunogen: A synthetic peptide mapping to the amino terminal domain of human beta-Actin. |
| Other Names | [actin, cytoplasmic 1; Actin, cytoplasmic 1; actin, cytoplasmic 1; PS1TP5-binding protein 1; beta cytoskeletal actin; actin, beta; Beta-actin], [ACTB; ACTB; BRWS1; PS1TP5BP1] |
| Gene, Accession # | Gene ID: 60, NCBI: NP_001092.1, UniProt: P60709 |
| Catalog # | MBS440061 |
| Price | $240 |
| Order / More Info | beta-Actin (A11) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.) Hoffrogge R, Mikkat S, Scharf C, Beyer S, Christoph H, Pahnke J, Mix E, Berth M, Uhrmacher A, Zubrzycki IZ, Miljan E, Volker U, Rolfs A. 2006. 2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM). Proteomics. Mar;6(6):1833-47. 2.) Dogan S, Hu X, Zhang Y, Maihle NJ, Grande JP, Cleary MP. 2007. Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice. Breast Cancer Res. 9(6):R91.1.Fuller CL, Braciale VL and Samelson LE. 2003. All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton. Immunol Rev. 191:220-236. 2.Giganti A and Friederich E. 2003. The actin cytoskeleton as a therapeutic target: state of the art and future directions. Prog Cell Cycle Res. 5:511-525. 3.Doolittle RF. 1995. The origins and evolution of eukaryotic proteins. Philos Trans Royal Soc London Biol Sci. 349(1329):235-240. 4.Maccioni RB and Cambiazo V. 1995. Role of microtubule-associated proteins in the control of microtubule assembly. Physiol Rev. 75(4):835-864. 5.Schutt CE, Rozycki MD, Myslik JC, Lindberg U. 1995. A discourse on modeling F-actin. J. Struct. Biol. 115:186-198. 6.Barkalow K and Hartwig JH. 1995. Actin cytoskeleton. Setting the pace of cell movement. Curr Biol. 5(9):1000-1002. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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