alpha Adaptin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | alpha Adaptin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: alpha Adaptin antibody detects endogenous levels of alpha Adaptin. Function: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein |
| Immunogen | Immunogen: A synthesized peptide derived from human alpha Adaptin. Subcellular Location: Cell Membrane. Membrane > Coated Pit. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. Tissue Specificity: Isoform A expressed in forebrain, skeletal muscle, spinal cord, cerebellum, salivary gland, heart and colon. Isoform B is widely expressed in tissues and also in breast cancer and in prostate carcinoma cells |
| Other Names | [100 kDa coated vesicle protein A; Adapter-related protein complex 2 alpha-1 subunit; adapter-related protein complex 2 subunit alpha-1; Adaptin alpha A; Adaptin alpha; Adaptor protein complex AP 2 alpha 1 subunit; adaptor protein complex AP 2 subunit alpha 1; Adaptor protein complex AP-2 subunit alpha-1; Adaptor protein complex AP2 alpha 1 subunit; adaptor protein complex AP2 subunit alpha 1; Adaptor related protein complex 2 alpha 1 subunit; Adaptor related protein complex AP 2 alpha 1 subunit; Adaptor related protein complex AP2 alpha 1 subunit; ADTAA; Alpha A adaptin; Alpha adaptin A; Alpha-adaptin A; alpha1 adaptin; Alpha1-adaptin; AP 2 alpha; AP 2 complex subunit alpha 1; AP-2 complex subunit alpha-1; AP2 complex subunit alpha 1; AP2-ALPHA; Ap2a1; AP2A1_HUMAN; CLAPA 1; CLAPA1; Clathrin adaptor complex AP2. alpha subunit; Clathrin assembly protein complex 2 alpha A large chain; Clathrin assembly protein complex 2 alpha-A large chain; Clathrin associated/assembly/adaptor protein large alpha 1; clathrin associated assembly adaptor protein large alpha 1; clathrin associated/assembly/adaptor protein, large, alpha 1; Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit; Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit] |
| Gene, Accession # | [AP2A1], Gene ID: 160, NCBI: NP_055018.2, UniProt: O95782 |
| Catalog # | MBS9603575 |
| Price | $240, $280 |
| Order / More Info | alpha Adaptin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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