Edit |   |
---|---|
Antigenic Specificity | Semaphorin 5A |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Me. Semaphorine 5A plays a role in autism, reducing the ability of neurons to form connections with other neurons in |
Immunogen | Immunogen: Peptide with sequence DEATKKACYSKGKS (corresponding to a part of the extra-cellular domain) from the internal region of the protein sequence according to NP_003957.1. |
Other Names | [semaphorin-5A; Semaphorin-5A; semaphorin-5A; semaphorin 5A; Semaphorin-F; Sema F], [SEMA5A; SEMA5A; semF; SEMAF; SEMAF; Sema F] |
Gene, Accession # | Gene ID: 9037, NCBI: NP_003957.2, UniProt: Q13591 |
Catalog # | MBS555929 |
Price | $440 |
Order / More Info | Semaphorin 5A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |