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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of Caspase 3. CASP3 (Caspase 3) is a Protein Coding gene. Diseases associated with CASP3 include Lung Cancer and Nervous System Cancer. Among its related pathways are AGE/RAGE pathway and p75 NTR receptor-mediated signalling. The protein encoded by CASP3 is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated |
Immunogen | Immunogen: Synthesized peptide derived from part region of human Caspase 3 protein |
Other Names | [Rabbit Caspase 3; Caspase-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1] |
Gene, Accession # | [CASP-3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
Catalog # | MBS9700777 |
Price | $250, $250 |
Order / More Info | Caspase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |