KHDRBS2 - middle region Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | KHDRBS2 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonist |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KHDRBS2 |
| Other Names | [KH domain-containing, RNA-binding, signal transduction-associated protein 2 isoform 2; KH domain-containing, RNA-binding, signal transduction-associated protein 2; KH domain-containing, RNA-binding, signal transduction-associated protein 2; KH RNA binding domain containing, signal transduction associated 2; Sam68-like mammalian protein 1; SLM-1; hSLM-1] |
| Gene, Accession # | [KHDRBS2], Gene ID: 202559, NCBI: NP_689901.2, UniProt: Q5VWX1 |
| Catalog # | MBS3222739 |
| Price | $335 |
| Order / More Info | KHDRBS2 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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