Edit |   |
Antigenic Specificity | HEF1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Enhancer of filamentation 1(NEDD9) detection. Tested with WB in Human. Background: Enhancer of filamentation 1 (EF1), also known as NEDD-9, is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. It is mapped to 6p24.2. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. |
Immunogen | Immunogen: E Coli-derived human HEF1 recombinant protein (Position: K273-E421). Human HEF1 shares 83% amino acid (aa) sequence identity with mouse HEF1. Ig Type: Rabbit IgG |
Other Names | [Enhancer of filamentation 1; CAS L; Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CASL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)); dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1)); dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1; NEDD 9; NEDD-9; NEDD9; NEDD9 protein; Neural cell expressed developmentally down regulated 9; Neural precursor cell expressed developmentally down regulated 9; Neural precursor cell expressed developmentally down-regulated protein 9; NY REN 12 antigen; p105; Protein NEDD9; Renal carcinoma antigen NY-REN-12; neural precursor cell expressed, developmentally down-regulated 9], [NEDD9; NEDD9; CAS2; CASL; HEF1; CAS-L; CASS2; CASL; CASS2; hEF1; CAS-L; CasL; NEDD-9] |
Gene, Accession # | [HEF1], Gene ID: 4739, NCBI: NP_001135865.1, UniProt: Q14511 |
Catalog # | MBS178099 |
Price | $280 |
Order / More Info | HEF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Law, S. F., Estojak, J., Wang, B., Mysliwiec, T., Kruh, G., Golemis, E. A. Human enhancer of filamentation 1, a novel p130(cas)-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Molec. Cell. Biol. 16: 3327-3337, 1996. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/4/2012. |