Human Nav1.5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Nav1.5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentration1ug/ul
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Rat-36/39 residues identical, mouse-34/39 residues identical. Voltage-gated Na+ channels (Nav) are responsible for myocardial conduction and maintenance of the cardiac rhythm and are essential for the generation of action potentials and cell excitability.1 Dysfunction or disregulation of cardiac sodium channels can cause several disorders, including cardiac arrhythmias. The majority of Na+ channels in the mammalian heart are Tetrodotoxin (TTX)-insensitive Nav1.5.2 The putative structure of NaV1.5 consists of four homologous domain (I-IV), each containing six transmembrane segments (S1-S6). Mutations in the C-terminus of NaV1.5 were described in connection to Long QT syndrome and Brugada syndrome.1-2 Recent data have demonstrate
ImmunogenImmunogen: GST fusion protein with residues 1978-2016 of human Nav1.5 (Accession# Q14524).
Other Names[Nav1.5, partial; sodium channel protein type 5 subunit alpha; sodium voltage-gated channel alpha subunit 5]
Gene, Accession #[Nav1.5], Gene ID: 6331
Catalog #MBS4159182
Price$725
Order / More InfoHuman Nav1.5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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