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Antigenic Specificity | Human Nav1.5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rat-36/39 residues identical, mouse-34/39 residues identical. Voltage-gated Na+ channels (Nav) are responsible for myocardial conduction and maintenance of the cardiac rhythm and are essential for the generation of action potentials and cell excitability.1 Dysfunction or disregulation of cardiac sodium channels can cause several disorders, including cardiac arrhythmias. The majority of Na+ channels in the mammalian heart are Tetrodotoxin (TTX)-insensitive Nav1.5.2 The putative structure of NaV1.5 consists of four homologous domain (I-IV), each containing six transmembrane segments (S1-S6). Mutations in the C-terminus of NaV1.5 were described in connection to Long QT syndrome and Brugada syndrome.1-2 Recent data have demonstrate |
Immunogen | Immunogen: GST fusion protein with residues 1978-2016 of human Nav1.5 (Accession# Q14524). |
Other Names | [Nav1.5, partial; sodium channel protein type 5 subunit alpha; sodium voltage-gated channel alpha subunit 5] |
Gene, Accession # | [Nav1.5], Gene ID: 6331 |
Catalog # | MBS4159182 |
Price | $725 |
Order / More Info | Human Nav1.5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |