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Antigenic Specificity | NTF97/Importin beta (835) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mL, 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nucleocytoplasmic transport, a signal-and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human IMB1 |
Other Names | [importin 1; importin 90; Importin Beta; importin beta-1 subunit; Importin subunit beta-1; Importin-90; Karyopherin; karyopherin (importin) beta 1; karyopherin beta 1; Karyopherin subunit beta-1; karyopherin, beta 1; NTF97; Nuclear factor p97; Nuclear Transport Factor p97; Pore targeting complex 97 kDa subunit; PTAC97; SCG; AA409963; IMB1; Impnb; IPO1; IPOB; KPNB1; NTF97], [KPNB1; KPNB1; IMB1; IPO1; IPOB; Impnb; NTF97; NTF97; PTAC97] |
Gene, Accession # | [IMB1], Gene ID: 3837, NCBI: NP_001263382.1, UniProt: Q14974 |
Catalog # | MBS435152 |
Price | $225, $350, $565 |
Order / More Info | NTF97/Importin beta (835) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |