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Antigenic Specificity | Phospho-Gab1 (Tyr406) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Gab1 (Tyr406) Antibody detects endogenous levels of Gab1 only when phosphorylated at Tyr406. Description: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).Post Translational Modifications: Phosphorylated in response to FGFR1 activation. Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Phosphorylated on tyrosine residues by HCK upon IL6 si |
Immunogen | Immunogen: A synthesized peptide derived from human Gab1 around the phosphorylation site of Tyr406. |
Other Names | [Gab 1; GAB1; GAB1_HUMAN; GRB 2 associated binder 1; GRB 2 associated binding protein 1; GRB2 associated binding protein 1 isoform a; GRB2 associated binding protein 1 isoform b; GRB2-associated binder 1; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1] |
Gene, Accession # | [Gab1], Gene ID: 2549, NCBI: NP_002030.2, UniProt: Q13480 |
Catalog # | MBS9610734 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Gab1 (Tyr406) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |