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Antigenic Specificity | LRPPRC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LRPPRC antibody detects endogenous levels of LRPPRC. Function: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the |
Immunogen | Immunogen: A synthesized peptide derived from human LRPPRC. Subcellular Location: Mitochondrion. Nucleus, Nucleoplasm. Nucleus Inner Membrane. Nucleus Outer Membrane. Seems to be predominantly mitochondrial. Tissue Specificity: Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes. Predicted Cross Reactivity: Pig, Bovine, |
Other Names | [130 kDa leucine-rich protein; gp130; Leucine-rich PPR motif-containing protein; Leucine-rich PPR-motif containing protein; LPPRC_HUMAN; LRP 130; lrpprc; mitochondrial] |
Gene, Accession # | [LRPPRC], Gene ID: 10128, NCBI: NP_573566.2, UniProt: P42704 |
Catalog # | MBS9603649 |
Price | $240, $280 |
Order / More Info | LRPPRC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |