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Antigenic Specificity | Human TPO (THPO) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TPO, known also as TSF (thrombopoiesis stimulating factor), for mediator substances that function as natural stimulators of megakaryocytopoiesis and thus, promote the differentiation of platelets. TPO stimulates an increase in the sizes and numbers of megakaryocytes. It also increases the number of small acetyl-cholinesterase positive cells that are early precursor cells of the megakaryocytic lineage. TPO is a protein of 332 amino acids that shows significant homology with Epo (erythropoietin) in its N-terminal domain. A comparison of human and porcine TPO sequences shows 83 % identity between the erythropoietin-like domains but only 67 % between the C- terminal domains. |
Immunogen | Source Note: Polyclonal TPO antibody was produced from sera of rabbits immunized with recombinant human TPO. |
Other Names | [Rabbit TPO (THPO) purified; Thrombopoietin; TPO; THPO; PAb], [THPO; MGDF; ML; MGDF] |
Gene, Accession # | [TPO], Gene ID: 7066, NCBI: NP_000451.1, UniProt: P40225 |
Catalog # | MBS551049 |
Price | $280, $385 |
Order / More Info | Human TPO (THPO) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |