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Antigenic Specificity | DNMT3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] |
Immunogen | Immunogen: A synthetic peptide of human DNMT3B Observed Molecular Weight: 96kDa |
Other Names | [ICF; ICF1; M.HsaIIIB] |
Gene, Accession # | [DNMT3B], Gene ID: 1789, NCBI: NP_001193985.1 |
Catalog # | MBS2529738 |
Price | $150, $225, $360 |
Order / More Info | DNMT3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |