Phospho-IP3 Receptor (Ser1756) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-IP3 Receptor (Ser1756) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-IP3 Receptor (Ser1756) antibody detects endogenous levels of IP3 Receptor only when phosphorylated at Ser1756. Function: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1, 4, 5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).Subunit Structure: Homotetramer. Interacts with TRPC4. The PPXXF motif binds HOM1, HOM2 a |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-IP3 Receptor (Ser1756) Subcellular Location: Endoplasmic Reticulum Membrane. Tissue Specificity: Widely expressed. |
| Other Names | [4; 5-trisphosphate receptor; 5-trisphosphate receptor type 1; DKFZp313E1334; DKFZp313N1434; inositol 1 4 5 triphosphate receptor type 1; Inositol 1 4 5 trisphosphate Receptor Type 1; Inositol 1; InsP3R1; IP3; IP3 receptor; IP3 receptor isoform 1; IP3R 1; IP3R; IP3R1; ITPR 1; Itpr1; ITPR1_HUMAN; SCA15; SCA16; SCA29; Type 1 inositol 1 4 5 trisphosphate receptor; Type 1 inositol 1; Type 1 InsP3 receptor] |
| Gene, Accession # | [ITPR1], Gene ID: 3708, NCBI: NP_001093422.2, UniProt: Q14643 |
| Catalog # | MBS9604463 |
| Price | $240, $280 |
| Order / More Info | Phospho-IP3 Receptor (Ser1756) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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