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Antigenic Specificity | Eps15 (Phospho Tyr849) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Eps15 (Y849) Polyclonal Antibody detects endogenous levels of Eps15 protein only when phosphorylated at Y849. EPS15 encodes epidermal growth factor receptor pathway substrate 15 that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, EPS15 is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from human Eps15 around the phosphorylation site of Y849 |
Other Names | [Rabbit Eps15 (phospho Tyr849); EPS15; AF1P; Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p] |
Gene, Accession # | [EPS15], Gene ID: 2060, NCBI: NP_001153441.1, UniProt: P42566 |
Catalog # | MBS9704783 |
Price | $130, $220, $325 |
Order / More Info | Eps15 (Phospho Tyr849) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |