Frizzled 6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFrizzled 6
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, monkey
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRecognizes endogenous levels of Frizzled 6 protein. Frizzled 6 is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.
ImmunogenImmunogen: Frizzled 6 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Frizzled 6 as the immunogen
Other Names[Purified Frizzled 6; Frizzled 6; Frizzled 6; Frizzled-6; Fz-6; hFz6]
Gene, Accession #[Fz-6], Gene ID: 8323
Catalog #MBS5315207
Price$270
Order / More InfoFrizzled 6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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