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Antigenic Specificity | Frizzled 6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of Frizzled 6 protein. Frizzled 6 is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. |
Immunogen | Immunogen: Frizzled 6 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Frizzled 6 as the immunogen |
Other Names | [Purified Frizzled 6; Frizzled 6; Frizzled 6; Frizzled-6; Fz-6; hFz6] |
Gene, Accession # | [Fz-6], Gene ID: 8323 |
Catalog # | MBS5315207 |
Price | $270 |
Order / More Info | Frizzled 6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |