Aggrecan/AGC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAggrecan/AGC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody recognizes ~250 kDa of human Aggrecan protein. It reacts with mouse. The other species are not tested. Aggrecan or aggregating chondroitin sulfate proteoglycan, is an integral part of the extracellular matrix in cartilagenous tissue. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular carti
Immunogenn/a
Other Names[Aggrecan], [ACAN; ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; AGC1; CSPG1; MSK16; CSPCP; Chondroitin sulfate proteoglycan 1]
Gene, Accession #[AGC1], Gene ID: 176, NCBI: AAD14816.1
Catalog #MBS460343
Price$265
Order / More InfoAggrecan/AGC1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSandy, J.D., et al. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. J. Clin. Invest. 89 (5), 1512-1516 (1992)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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