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Antigenic Specificity | AIF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AIF antibody detects endogenous levels of AIF protein. Not tested with other proteins. This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene. |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | n/a |
Gene, Accession # | [AIF] |
Catalog # | MBS416590 |
Price | $230 |
Order / More Info | AIF Antibody from MYBIOSOURCE INC. |
Product Specific References | Kim,J.T., Kim,K.D., Song,E.Yet al. Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3subunit p44 (eIF3g). FEBS Lett. 580 (27), 6375-6383 (2006) |