Phospho-CrkII (Tyr221) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CrkII (Tyr221) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-CrkII (Tyr221) Antibody detects endogenous levels of Phospho-CrkII (Tyr221). The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-CrkII (Tyr221) |
| Other Names | [Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; CRK; CRKII; Proto-oncogene c-Crk] |
| Gene, Accession # | [CrkII], Gene ID: 1398, NCBI: NP_005197.3, UniProt: P46108 |
| Catalog # | MBS4750399 |
| Price | $335 |
| Order / More Info | Phospho-CrkII (Tyr221) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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