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Antigenic Specificity | JAK2 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: chicken, mouse, porcine, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This JAK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 834-868 amino acids from the C-terminal region of human JAK2. Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors, phosphorylates specif |
Immunogen | n/a |
Other Names | [Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2; JAK2] |
Gene, Accession # | [JAK2], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674 |
Catalog # | MBS9209716 |
Price | $165, $370 |
Order / More Info | JAK2 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Saltzman A.,et al.Biochem. Biophys. Res. Commun. 246:627-633(1998). Dalal I.,et al.Blood 91:844-851(1998). Peeters P.,et al.Blood 90:2535-2540(1997). Humphray S.J.,et al.Nature 429:369-374(2004). Pollack B.P.,et al.J. Biol. Chem. 274:31531-31542(1999). |