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Antigenic Specificity | A-Actinin |
Clone | 4A12 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: a-actinin Monoclonal Antibody(4A12) detects endogenous levels of ACTN1. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actin |
Immunogen | Immunogen: Recombinant Protein of a-actinin of ACTN1 |
Other Names | [Mouse a-actinin (4A12)] |
Gene, Accession # | [ACTN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814 |
Catalog # | MBS9700497 |
Price | $130, $220, $325 |
Order / More Info | A-Actinin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |