A-Actinin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityA-Actinin
Clone4A12
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: a-actinin Monoclonal Antibody(4A12) detects endogenous levels of ACTN1. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actin
ImmunogenImmunogen: Recombinant Protein of a-actinin of ACTN1
Other Names[Mouse a-actinin (4A12)]
Gene, Accession #[ACTN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814
Catalog #MBS9700497
Price$130, $220, $325
Order / More InfoA-Actinin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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