Acinus Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAcinus
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionAcinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified
ImmunogenImmunogen: Acinus antibody was raised against a peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17, which are identical to those of mouse Acinus. Buffer: Acinus Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[ACN; ACINUS; fSAP152; KIAA0670; Apoptotic chromatin condensation inducer in the nucleus; Acinus; apoptotic chromatin condensation inducer 1], [ACIN1; ACIN1; ACN; ACINUS; fSAP152; ACINUS; KIAA0670; Acinus]
Gene, Accession #[ACIN1], Gene ID: 22985, NCBI: AAD56724, UniProt: Q9UKV3
Catalog #MBS150378
Price$375
Order / More InfoAcinus Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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