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Antigenic Specificity | Human MHC Class II |
Clone | [TDR31.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | no preservative |
Size | 0.1 mg |
Concentration | 1.0 mg/ml |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC)(FS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Information: Human MHC Class II (HLA-DP, DQ & DR) molecules are expressed on dendritic cells, monocytes, macrophages, and myeloid cells. MHC Class II molecules are heterodimers of polymorphic transmembrane a and b chains and generally bind exogenously derived peptides of about 10-17 amino acids. MHC Class II molecules interact with the T cell receptor on CD4 T cells. Antibody TDR31.1 recognizes a monomorphic class II b chain epitope |
Immunogen | Immunogen: Purified class II from JY cell line |
Other Names | [human MHC Class II beta chain (HLA-DP, DQ & DR)], [HLA-DQB1; HLA-DQB1; IDDM1; CELIAC1; HLA-DQB; HLA-DQB] |
Gene, Accession # | Gene ID: 3119, NCBI: AAA85335.1 |
Catalog # | MBS666161 |
Price | $270 |
Order / More Info | Human MHC Class II Antibody from MYBIOSOURCE INC. |
Product Specific References | T.A. de Kretser, et al, (1982) Eur J Immunol 12: 214-221. R. Busch & J.B. Rothbard, (1990) J Immunol Methods 134: 1-22. K.W. Wacherpfennig & J.L. Strominger, (1995) J Exp Med 181:161-168. |