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Antigenic Specificity | LRP4 |
Clone | [S164-6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects the cytoplasmic domain of LRP4 ~215 kDa, small degradation products ~100kD. Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. |
Immunogen | Immunogen: Fusion protein amino acids 1747-1905 (cytoplasmic C-terminus) of mouse LRP4 |
Other Names | [Mouse Mouse LRP4 (Cytoplasmic) IgG1; LRP4 (Cytoplasmic) : APC/Cy7; Corin; KIAA0816; LDLR; LDLR dan; Low density lipoprotein receptor related protein 4; LRP-4; LRP10; MEGF7; Multiple epidermal growth factor like domains 7] |
Gene, Accession # | [LRP4], Gene ID: 228357, NCBI: NP_766256.3, UniProt: Q8VI56 |
Catalog # | MBS8003184 |
Price | $510 |
Order / More Info | LRP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353-92. |