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Antigenic Specificity | TIFA (N-term), 52-79 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.32 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TIFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from the N-terminal region of human TIFA. Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. |
Immunogen | n/a |
Other Names | [TRAF-interacting protein with FHA domain-containing protein A; Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding protein; TIFA; T2BP] |
Gene, Accession # | [TIFA], Gene ID: 92610, NCBI: NP_443096.1, UniProt: Q96CG3 |
Catalog # | MBS9202761 |
Price | $165, $370 |
Order / More Info | TIFA (N-term), 52-79 Antibody from MYBIOSOURCE INC. |
Product Specific References | Minoda, Y., et al. Biochem. Biophys. Res. Commun. 344(3):1023-1030(2006) ?Ea, C.K., et al. Proc. Natl. Acad. Sci. U.S.A. 101(43):15318-15323(2004) ?Matsuda, A., et al. Oncogene 22(21):3307-3318(2003) ?Takatsuna, H., et al. J. Biol. Chem. 278(14):12144-12150(2003) |