Fli-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFli-1
Clone[G146-22]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted)
Concentrationn/a
Applicationsn/a
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DescriptionFli-1 protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Approximately 90% of Ewing's Sarcoma/Primitive Neuroectodermal Tumors (ES/PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein, which can be detected by this antibody. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. Fli-1 has been found to be expressed in the great majority of vascular tumors including Angiosarcomas, Hemangioendotheliomas, Hemangiomas, and Kaposi's Sarcomas. It has been reported that the high sensitivity and specificity of Fli-1 is equal to or exceeds that of the estab
Immunogenn/a
Other Names[FLI-1; Friend leukemia integration 1 transcription factor; Proto-oncogene Fli-1; Transcription factor ERGB], [FLI-1; FLI1]
Gene, Accession #[Fli-1], NCBI: CAA76731.1, UniProt: Q01543
Catalog #MBS373012
Price$130, $195, $205
Order / More InfoFli-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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