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Antigenic Specificity | Mouse CD206 |
Clone | [MR5D3] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.25 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS)*, Immunohistochemistry - Frozen (IHC-F), Immunoprecipitation (IP), Immunofluorescence (IF). *CD206 is expressed weakly at the cell surface. Staining may be increased following membrane permeabilisation. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti mouse CD206 antibody, clone MR5D3 recognizes the mouse mannose receptor, a ~175 kDa type 1 membrane glycoprotein that is also known as CD206. CD206 is expressed on most tissue macrophages, certain endothelial cells and in vitro derived dendritic cells (Zamze et al. 2002). The mannose receptor, CD206, is composed of a N-terminal cysteine-rich domain, a fibronectin type II domain, eight tandemly arranged C-type lectin domains (CTLD), a transmembrane domain, and a cytoplasmic domain. The terminal cysteine-rich domain binds sulfated sugars, and the CTLD recognizes carbohydrates terminating in mannose, fucose and N-acetylglucosamine, all sugars found on microorganisms and on some endogenous proteins (Su et al. 2005). Rat anti mou |
Immunogen | Immunogen: Chimaeric CRD4-7-Fc protein. Fusion Partners: Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line. Shelf Life: 18 months from date of dispatch. |
Other Names | [macrophage mannose receptor 1; Macrophage mannose receptor 1; macrophage mannose receptor 1; MMR; mannose receptor, C type 1; CD_antigen: CD206], [Mrc1; Mrc1; MR; CD206; AW259686; MMR] |
Gene, Accession # | [CD206], Gene ID: 17533, NCBI: NP_032651.2 |
Catalog # | MBS215657 |
Price | $475 |
Order / More Info | Mouse CD206 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |