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Antigenic Specificity | DR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 10A(TNFRSF10A) detection. Tested with WB in Human. Background: TNFRSF10A(Tumor Necrosis Factor Receptor Subfamily Member 10A), also known as APO2, DR4 or TRAILR1, is a protein that in humans is encoded by the TNFRSF10A gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. By analysis of radiation hybrids, Marsters et al.(1997) mapped the DR4 gene to 8p21. The TRAIL receptor DR5, and 2 decoy receptors for TRAIL, DCR1, and DCR2, are located in the same region, suggesting that these receptors arose from recent gene duplication events. Pan et al.(1997) found that, as with FAS, TNFR1, and DR3, overexpression of DR4 indu |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DR4 (110-125aa TIKLHDQSIGTQQWEH). |
Other Names | [Tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily, member 10a; Apo 2; Apo2; CD 261; CD261; CD261 antigen; Cytotoxic ligand TRAIL receptor; Cytotoxic TRAIL receptor; Death receptor 4; DR 4; DR4; MGC9365; NF related apoptosis-inducing ligand receptor 1; T10A; TNF related apoptosis inducing ligand receptor 1; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TR10A_HUMAN; TRAIL R1; TRAIL receptor 1; TRAIL-R1; TRAILR 1; TRAILR1; Tumor necrosis factor receptor superfamily member 10a; Tumor necrosis factor receptor superfamily member 10A precursor], [TNFRSF10A; TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1; APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1] |
Gene, Accession # | [TNFRSF10A], Gene ID: 8797, NCBI: O00220.3, UniProt: O00220 |
Catalog # | MBS176231 |
Price | $280 |
Order / More Info | DR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |