AIF Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AIF |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, human, mouse, rat |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | AIF (apoptosis-inducing factor) was initially discovered as a protein involved in caspase-independent cell death. It is now known that AIF has both vital and lethal functions (reviewed in Modjtahedi et al, 2006). In healthy cells, AIF is a flavoprotein present in the mitochondria where it has vital roles in cellular redox metabolism and mitochondrial bioenergetics. In many models of apoptosis, AIF is released from the mitochondria during mitochondrial outer membrane permeabilization along with other mitochondrial proteins. Upon release, AIF translocates first to the cytosol and then to the nucleus where it induces chromatin condensation and DNA degradation. Although several lines of evidence suggest that AIF is a main mediator of capsase-in |
| Immunogen | Immunogen Information: A synthetic peptide of human AIF (amino acids 151-169 RARDPGARVLIVSEDPELP) was used as immunogen for this antibody |
| Other Names | [AIFM1; AIF; PDCD8; Programmed cell death protein 8; to AIF; AIF; AIF], [AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8] |
| Gene, Accession # | [AIF], Gene ID: 9131, NCBI: O95831.1, UniProt: O95831 |
| Catalog # | MBS668494 |
| Price | $270 |
| Order / More Info | AIF Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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