Edit |   |
---|---|
Antigenic Specificity | RTN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. |
Immunogen | Immunogen: A synthetic peptide of human RTN3 Immunogen Species: Human |
Other Names | [ASYIP; HAP; NSPL2; NSPLII; RTN3-A1] |
Gene, Accession # | [RTN3], Gene ID: 10313, NCBI: NP_001252518.1, UniProt: O95197 |
Catalog # | MBS9135115 |
Price | $200, $275, $430 |
Order / More Info | RTN3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |