PLEKHM1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PLEKHM1 antibody, protein, ELISA kits.
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| Antigenic Specificity | PLEKHM1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PLEKHM1 is a member of the M family of Pleckstrin homolog domain-containing proteins, a group of proteins containing a RUN domain, two pleckstrin homology domains, and a cysteine-rich domain. It was identified through segregation analysis as a cause of osteopetrosis in humans. PLEKHM1 co-localizes with Rab7 to late endosomal/lysosomal vesicles in HEK293 and osteoclast-like cells, with this co-localization dependent on the prenylation of Rab7. Monocytes from a patient homozygous for a mutated form of PLEKHM1differentiated into osteoclasts normally, but failed to form ruffled borders and showed little evidence of bone resorbtion when cultured on dentine discs. Another mutation of PLEKHM1 impaired vesicular acidification and increased TRACP se |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against an 18 amino acid peptide from near the amino terminus of human PLEKHM1. |
| Other Names | [Pleckstrin homolog domain containing family M member 1, OPTB6, B2, AP162] |
| Gene, Accession # | [PLEKHM1], Gene ID: 9842, NCBI: NP_055613.1, UniProt: Q9Y4G2 |
| Catalog # | MBS9407815 |
| Price | $320 |
| Order / More Info | PLEKHM1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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