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Antigenic Specificity | HTR1D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HTR1D antibody detects endogenous levels of total HTR1D. Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.Subunit |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane; Multipass Membrane Protein Tissue Specificity: Detected in brain neocortex and caudate nucleus (at protein level). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Chicken Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Chicken (89%) |
Other Names | [5 HT 1D alpha; 5 HT 1D; 5 HT1B; 5 HT1D; 5 hydroxytryptamine (serotonin) receptor 1B; 5 hydroxytryptamine (serotonin) receptor 1D G protein coupled; 5 hydroxytryptamine 1B receptor (5 HT 1B) (Serotonin receptor) (5 HT 1D beta) (Serotonin 1D beta receptor) (S12); 5 hydroxytryptamine receptor 1D; HT1DA; HTR1D; HTR1D2; HTR1DA; HTRL; RDC4; S12; Serotonin receptor 1D] |
Gene, Accession # | [HTR1D], Gene ID: 3352, NCBI: NP_000855.1, UniProt: P28221 |
Catalog # | MBS9604220 |
Price | $240, $280 |
Order / More Info | HTR1D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |