TEAD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTEAD2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); Immunohistochemistry (IHC); Immunofluorescence (IF); Immunocytochemistry (ICC)
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DescriptionRecognizes endogenous levels of TEAD2 protein. Polyclonal antibody to detect endogenous levels of TEAD2 in human and mouse. Transcription factor which plays a key role in the Hippo signaling pathway; a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2; in complex with its regulatory protein SAV1; phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1; which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ; thereby regulating cell proliferation; migration and epithelial mesenchymal transition (EMT) ind
ImmunogenImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TEAD2
Other Names[TEF4; Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2], [TEAD2; TEAD2; ETF; TEF4; TEF-4; TEAD-2; TEF4; TEAD-2]
Gene, Accession #[TEAD2], Gene ID: 8463, NCBI: NP_001243587.1, UniProt: Q15562
Catalog #MBS846045
Price$345
Order / More InfoTEAD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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