Edit |   |
---|---|
Antigenic Specificity | TEAD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC); Immunofluorescence (IF); Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of TEAD2 protein. Polyclonal antibody to detect endogenous levels of TEAD2 in human and mouse. Transcription factor which plays a key role in the Hippo signaling pathway; a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2; in complex with its regulatory protein SAV1; phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1; which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ; thereby regulating cell proliferation; migration and epithelial mesenchymal transition (EMT) ind |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TEAD2 |
Other Names | [TEF4; Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2], [TEAD2; TEAD2; ETF; TEF4; TEF-4; TEAD-2; TEF4; TEAD-2] |
Gene, Accession # | [TEAD2], Gene ID: 8463, NCBI: NP_001243587.1, UniProt: Q15562 |
Catalog # | MBS846045 |
Price | $345 |
Order / More Info | TEAD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |