Phospho-MAP2K1-S297 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAP2K1-S297
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB)
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DescriptionMEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. MEK1/2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx (1-4). Constitutively active forms of MEK1/2 are sufficient for the transformation of NIH/3T3 cells or the differentiation of PC-12 cells (4). MEK activates p44 and p42 MAP kinase by phosphorylating both threonine and tyrosine residues at sites loc
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S297 of human MAP2K1 Observed Molecular Weight: 43kDa
Other Names[MEK1; MKK1; MAPKK1; PRKMK1]
Gene, Accession #[MAP2K1-S297]
Catalog #MBS2523211
Price$110, $150, $225
Order / More InfoPhospho-MAP2K1-S297 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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