SET07 (C-term), 362-393 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SET07 (C-term), 362-393 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SET07 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-393 amino acids from the C-terminal region of human SET07. SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upst |
| Immunogen | n/a |
| Other Names | [N-lysine methyltransferase SETD8; 211-; H4-K20-HMTase SETD8; Histone-lysine N-methyltransferase SETD8; Lysine N-methyltransferase 5A; PR/SET domain-containing protein 07; PR-Set7; PR/SET07; SET domain-containing protein 8; SETD8; KMT5A; PRSET7; SET07; SET8] |
| Gene, Accession # | [SETD8], Gene ID: 387893, NCBI: NP_065115.3, UniProt: Q9NQR1 |
| Catalog # | MBS9207710 |
| Price | $165, $370 |
| Order / More Info | SET07 (C-term), 362-393 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nishioka, K., et al., Mol. Cell 9(6):1201-1213 (2002). Fang, J., et al., Curr. Biol. 12(13):1086-1099 (2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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