PYCARD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPYCARD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen: Recombinant protein of human PYCARD Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[ASC; CARD5; TMS; TMS-1; TMS1]
Gene, Accession #[PYCARD], Gene ID: 29108, NCBI: NP_037390.2, UniProt: Q9ULZ3
Catalog #MBS8535457
Price$300
Order / More InfoPYCARD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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