Human Non-POU domain-containing octamer-binding protein Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Non-POU domain-containing octamer-binding protein
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionDNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. Together with PSPC1, required for the formation of nuclear paraspeckles. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs. The SFPQ-NONO heteromer may be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1. The SFPQ-NONO heteromer may be involved in DNA non-homologous end joi
ImmunogenImmunogen: Recombinant human Non-POU domain-containing octamer-binding protein(1-300aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23249 / sc-23247 / sc-46223 / sc-46221 / sc-46220 / sc-67016
Other Names[NonO protein; 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex; 52 kDa subunit; NMT55; p54(nrb); p54nrb; NONO; NRB54], [NONO; NONO; P54; NMT55; NRB54; P54NRB; PPP1R114; NRB54; NonO protein; p54nrb]
Gene, Accession #[NONO], Gene ID: 4841, NCBI: NP_001138880.1, UniProt: Q15233
Catalog #MBS1495004
Price$120, $160
Order / More InfoHuman Non-POU domain-containing octamer-binding protein Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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