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Antigenic Specificity | PRKAG3 (C-term), 426-454 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-454 amino acids from the C-terminal region of human PRKAG3. The protein encoded by this gene is a regulatory subunitof the AMP-activated protein kinase (AMPK). AMPK is a heterotrimerconsisting of an alpha catalytic subunit, and non-catalytic betaand gamma subunits. AMPK is an important energy-sensing enzyme thatmonitors cellular energy status. In response to cellular metabolicstresses, AMPK is activated, and thus phosphorylates andinactivates acetyl-CoA carboxylase (ACC) and beta-hydroxybeta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved inregulating de novo biosynthesis of fatty acid and c |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase subunit gamma-3; AMPK gamma3; AMPK subunit gamma-3; PRKAG3; AMPKG3] |
Gene, Accession # | [PRKAG3], Gene ID: 53632, NCBI: NP_059127.2, UniProt: Q9UGI9 |
Catalog # | MBS9210010 |
Price | $165, $370 |
Order / More Info | PRKAG3 (C-term), 426-454 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010) Jassim, G., et al. Pharmacopsychiatry (2010) In press : Crawford, S.A., et al. Diabetologia 53(9):1986-1997(2010) Ramanathan, L., et al. Protein Expr. Purif. 70(1):13-22(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) |