CD105 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD105
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CD105 antibody detects endogenous levels of total CD105. Function: Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830). Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8
ImmunogenImmunogen: A synthesized peptide derived from human CD105 Subcellular Location: Membrane. Tissue Specificity: Detected on umbilical veil endothelial cells (PubMed:10625079). Detected in placenta (at protein level) (PubMed:1692830). Detected on endothelial cells (PubMed:1692830). Predicted Cross Reactivity: Pig, Horse, Sheep, Dog Similarity: Pig (90%), Horse (90%), Sheep (90%), Dog (80%)
Other Names[AI528660; AI662476; CD 105; CD105; CD105 antigen; EGLN_HUMAN; END; Endoglin; Eng; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; S-endoglin; SN6]
Gene, Accession #[CD105], Gene ID: 2022, NCBI: NP_000109.1, UniProt: P17813
Catalog #MBS9608314
Price$240, $280
Order / More InfoCD105 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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