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Antigenic Specificity | Human HLA class II histocompatibility antigen, DRB1-3 chain |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules; and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-o |
Immunogen | Immunogen: Recombinant human HLA class II histocompatibility antigen, DRB1-3 chain protein |
Other Names | [Clone P2-beta-3; MHC class II antigen DRB1*3; HLA-DRB1], [HLA-DRB1; HLA-DRB1; SS1; DRB1; DRw10; HLA-DRB; HLA-DR1B] |
Gene, Accession # | [DRB1-3], Gene ID: 3123, NCBI: NP_001230894.1, UniProt: P01912 |
Catalog # | MBS1488288 |
Price | $160, $235 |
Order / More Info | Human HLA class II histocompatibility antigen, DRB1-3 chain Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |