EMA, Epithelial Membrane Antigen Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | EMA, Epithelial Membrane Antigen |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 1 mL |
| Concentration | 40 ug/ml |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The E29 antibody can be used for the detection of tumours of epithelial origin. Also squamous cell carcinoma will be stained by E29 especially when derived from the epidermis (which is unreactive in normal tissue). Frequently E29 has been use in parallel to antibodies against cytokeratins, HEA125 (Ep-CAM) or CEA. The antibody binds also to lymphoidal neoplasms e.g. anaplastic large cell lymphomas, which are also CD30 (Ki-1) positive. EMA, Epithelial Membrane Antigen belongs to a group of glycosylated proteins with a molecular mass between 259 and 400 kDa, which are known as human milk fat globules (HMFG). Except in milk fat these membrane proteins have been found in a number of epithelia. The antibody E29 shows high similarity to the reacti |
| Immunogen | Immunogen: Delipidised milkfat extract |
| Other Names | n/a |
| Gene, Accession # | [EMA] |
| Catalog # | MBS397200 |
| Price | $520 |
| Order / More Info | EMA, Epithelial Membrane Antigen Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cordell J., Richardson T.C., Pulford K.A.F., Ghosh A.K., Gatter K.C., Heydermann E., et al. (1985) Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemisty. Br. J. Cancer 52; 347-354. 2. Heydermann E., Strudley I., Powell G., Richardson T.C., Cordell J.L., and Mason D.Y. (1985) A new monoclonal antibody to epithelial membrane antigen (EMA)-E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2. Br. J. Cancer 52; 355-361. 3. Pinkus G.S., Etheridge C.L., and O'Connor E.M. (1986) Are keratin proteins a better tumor marker than epithelial membrane antigen? Am. J. Clin. Pathol. 85; 269-277. 4. Delsol G., Al Saati T., Gatter K.C., Gerdes J., Schwarting R., Caveriviere P., et al. (1988) Coexpression of epithelial membrane antigen (EMA), Ki-1, and interleukin-2 receptor by anaplastic large cell lymphomas. Am. J. Pathol. 130; 59-70. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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